Exercise-associated muscle cramps (EAMCs) are painful, involuntary contractions of a skeletal muscle during or shortly after exercise. Exercise-associated cramps typically occur in muscles that span multiple joints and are frequently used during exercise (eg, quadriceps).1 Severity ranges from a “cramp-prone state” to mild (ie, usually self-treatable and not limiting exercise performance) to serious (require exercise cessation, occur with other systemic signs or symptoms requiring medical intervention)
